Anchor Health's Downsize ingredients are:

• Chromium
  This essential trace element is required by the body in the metabolism of protein, fat, and carbohydrates.
  
  Although not yet conclusive, studies have also suggested that chromium supplementation may help increase muscle mass and reduce fat, possibly by boosting metabolism and increasing the efficiency of insulin in transporting glucose to the body's cells.
  
  
• (-) HCA Alpha Hydroxy Citric Acid
  Alpha hydroxy citric acid (HCA) is the active ingredient of the Indian fruit Garcinia cambogia. The rind of garcinia is especially rich in HCA, which is believed to help weight loss by blocking the conversion of starches and sugary food into fat. Studies have also suggested that HCA can help regulate and suppress appetite.
  
  
• Gymnema Sylvestre
  Another herb of Indian origin, gymnema is a climbing vine used in traditional Ayurvedic medicine to help digestion and weight loss.
  
  The active ingredient of gymnema, called gymnemic acid, can block sugar receptors in the taste buds, thereby suppressing the cravings for sweet taste as well as the sugar receptors in the intestine, to prevent absorption.
  
  Gymnema extract has also been suggested to help lower and maintain a healthy cholesterol level.
  
  
• Vanadyl Sulfate
  Derived from the trace mineral vanadium, vanadyl sulfate can help the body's regulation of healthy blood sugar levels. Vanadyl sulfate encourages the use of proteins and carbohydrates in the muscles, rather than their conversion to fat.
  
  

Select Scientific References

• Anderson RA. Effects of chromium on body composition and weight loss. Nutr Rev 1998; 56(9):266-70.
• McCarty MF. Chromium and other insulin sensitizers may enhance glucagon secretion: implications for hypoglycemia and weight control. Med Hypotheses 1996; 46(2):77-80.
• Preuss HG, et al. Efficacy of a noval calcium/potassium salt of (-)-hydroxycitric acid in weight control. Int J Clin Pharmacol Res 2005; 25(3):133-44.
• Jena BS, et al. Chemistry and biochemistry of (-)-hydroxycitric acid from Garcinia. J Agric Food Chem 2002; 5(1):10-22.
• Jiang H. Advances in the study on hypoglycemic constituents of Gymnema sylvestre (Retz.) Schult. Zhong Yao Cai 2003; 26(4):305-7.